Akademik Veri Yönetim Sistemi
BIRTH DEFECTS RESEARCH, cilt.112, sa.8, ss.633-639, 2020 (SCI-Expanded)
Objective To demonstrate major congenital abnormalities delivered or terminated at our institution between 2014 and 2018. Materials and Methods Necessary information was retrieved from the registries of the delivery room and electronic database of Hacettepe University Hospital, Ankara. Results This study was consisted of 307 major congenital anomalies. The incidence of major congenital anomalies was 2.9 per 1,000 live births, while the majority of the cases were related to cardiovascular, central nervous system, and diaphragmatic hernia with 97, 87, and 25 cases at each group, respectively. Rate of termination of pregnancy (TOP) and live birth were 35.1 and 59.2%, respectively. The overall infant mortality rate was 28.9% in cases with live birth, while this rate was highest in cardiovascular system abnormalities and diaphragmatic hernia. Out of 182 newborns, 92.8% admitted to the neonatal intensive care unit after the delivery. Median gestational week at TOP was 21(20). Conclusion We have shown that TOP and infant mortality rates were 35.1 and 28.9%, respectively in pregnancies with fetal malformations. Detailed multidisciplinary counseling must be provided for parents in pregnancies with major congenital abnormalities.