Effect of low-dose N-acetyl-cysteine infusion on tourniquet-induced ischaemia-reperfusion injury in arthroscopic knee surgery
ACTA ANAESTHESIOLOGICA SCANDINAVICA, cilt.49, sa.6, ss.847-851, 2005 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 49 Sayı: 6
- Basım Tarihi: 2005
- Doi Numarası: 10.1111/j.1399-6576.2005.00722.x
- Dergi Adı: ACTA ANAESTHESIOLOGICA SCANDINAVICA
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.847-851
- Hacettepe Üniversitesi Adresli: Evet
Özet
Background: Temporary occlusion of blood flow is used during arthroscopic knee surgery in order to provide a bloodless surgical field. The resulting ischaemia-reperfusion causes lipid peroxidation, which contributes to tissue injury. The aim of the study was to investigate the effect of low-dose n-acetyl cysteine (NAC) infusion on oxidative stress by determining malondialdehyde (MDA) levels during arthroscopic knee surgery.