B lymphocyte subsets and outcomes in patients with an initial diagnosis of transient hypogammaglobulinemia of infancy


Eroglu F. K. , Kaya F. S. F. , Cagdas D. N. , Ozgur T. T. , Yılmaz T., Tezcan I., ...More

SCANDINAVIAN JOURNAL OF IMMUNOLOGY, vol.88, no.4, 2018 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 88 Issue: 4
  • Publication Date: 2018
  • Doi Number: 10.1111/sji.12709
  • Title of Journal : SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Abstract

PurposeTransient hypogammaglobulinemia of infancy (THI) is a common immunodeficiency, but definitive diagnosis can only be made retrospectively. While the pathogenesis is still unknown, abnormalities have been reported in the B cell compartment. In this study, we analysed the B cell subsets of patients with an initial THI diagnosis (n=20) and compared them with those of healthy age-matched Turkish children (n=72).