Differential Diagnosis of Fever and Generalized Lymphadenopathy: An Interesting Case Report


Onal E. D., DURUSU TANRIÖVER M., ÖNAL İ. K., Sardan Y. C.

TURKIYE KLINIKLERI TIP BILIMLERI DERGISI, cilt.29, sa.4, ss.1032-1034, 2009 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 29 Sayı: 4
  • Basım Tarihi: 2009
  • Dergi Adı: TURKIYE KLINIKLERI TIP BILIMLERI DERGISI
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1032-1034
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Generalized lymphadenopathy is defined as enlargement of more than two noncontiguous lymph node groups. Sometimes it can be a real diagnostic challenge to the physician because the associated diseases clinically and pathologically may mimic each other. The differential diagnosis is important because each cause necessitates a different therapeutic approach. Associated diseases include infections, malignancies, autoimmune diseases, benign hyperplasia, storage diseases, and drug reactions. Here we presented a patient who developed fever and lymphadeopathy after phenytoin use but whose clinical presentation was later found to be secondary to Epstein-Barr virus (EBV) infection. We discussed the differential diagnosis between drug reaction and EBV infection as a cause of generalized lymphadenopathy.