Liver manifestations of cystic fibrosis

Akata D., Akhan O.

EUROPEAN JOURNAL OF RADIOLOGY, vol.61, no.1, pp.11-17, 2007 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 61 Issue: 1
  • Publication Date: 2007
  • Doi Number: 10.1016/j.ejrad.2006.11.008
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.11-17
  • Hacettepe University Affiliated: Yes


Chronic liver disease is one of the major complications of cystic fibrosis (CF). Significant liver disease is seen in 13-25% of children with CF. Improved life expectancy and prolonged follow-up have favored better characterization of the hepatic manifestations of CF and allowed direct observation of an increasing number of liver-related events. Liver disease typically develops in the first decade of life, with the incidence dropping rapidly after the age of 10 years. The wide spectrum of liver disease ranging from asymptomatic gallbladder abnormalities to biliary cirrhosis will be reviewed in this article. (C) 2006 Published by Elsevier Ireland Ltd.