Infection with Fasciola hepatica

Aksoy D., Kerimoglu U., Oto A., Erguven S., Arslan S., ÜNAL S., ...More

CLINICAL MICROBIOLOGY AND INFECTION, vol.11, no.11, pp.859-861, 2005 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Editorial Material
  • Volume: 11 Issue: 11
  • Publication Date: 2005
  • Doi Number: 10.1111/j.1469-0691.2005.01254.x
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.859-861
  • Keywords: diagnosis, Fasciola hepatica, fascioliasis, liver fluke, treatment, DIAGNOSIS


Fascioliasis, caused by the liver fluke Fasciola hepatica, is an infection that occurs worldwide, although humans are accidental hosts. F. hepatica infection comprises two stages, hepatic and biliary, with different signs and symptoms. Stool examination and ELISA can be used for the initial diagnosis. Radiographic techniques, such as computerised tomography and ultrasonography, as well as magnetic resonance imaging, are used widely for confirmation and follow-up of the disease. Invasive techniques, such as percutaneous cholangiography, endoscopic retrograde cholangiography and liver biopsy, may aid in the diagnosis but are not essential. Triclabendazole is recommended as the first-line agent for the treatment of F. hepatica infection, with bithionol as an alternative.