Systemic treatment in breast-cancer patients with brain metastasis

Arslan C., DİZDAR Ö., Altundag K.

EXPERT OPINION ON PHARMACOTHERAPY, cilt.11, sa.7, ss.1089-1100, 2010 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 11 Sayı: 7
  • Basım Tarihi: 2010
  • Doi Numarası: 10.1517/14656561003702412
  • Dergi Adı: EXPERT OPINION ON PHARMACOTHERAPY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1089-1100
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Areas covered in this review: Standard therapy for brain metastasis is currently whole-brain radiotherapy. Other treatment modalities include surgery and radiosurgery in selected cases, corticosteroids, and systemic chemotherapy. Little progress has been made in chemotherapy for the treatment of brain metastases, partly because tumors develop brain metastases at a stage when they become totally chemoresistant. Nevertheless, new treatment choices have emerged considering cytotoxic and biological agents for the treatment of CNS metastases in patients with breast cancer.