Is serum high-mobility group box 1 (HMGB-1) level correlated with liver fibrosis in chronic hepatitis B?

İNKAYA A. Ç., Demir N. A., Kolgelier S., Sumer S., Demir L. S., Ural O., ...Daha Fazla

MEDICINE, cilt.96, sa.36, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 96 Sayı: 36
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1097/md.0000000000007547
  • Dergi Adı: MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: alarmin molecules, chronic hepatitis B, high-mobility group box 1, liver fibrosis, STELLATE CELLS, VIRUS INFECTION, PROTEIN, FAILURE, ALARMINS, MARKER, INJURY
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Background: High-mobility group box 1 (HMGB1), identified as an alarmin molecule, was shown to have a role in virus-triggered liver injury. We aimed to evaluate the association between serum levels of HMGB1 and liver fibrosis.