Time dependent change of ethanol consumption biomarkers, ethyl glucuronide and ethyl sulphate, after single dose ethanol intake


Karacaoglu E., Odabasi A. B. , AKÇAN R., TÜMER A. R. , Lale A., KOCADAĞLI T., ...More

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, vol.44, no.3, pp.379-387, 2019 (Peer-Reviewed Journal) identifier identifier

  • Publication Type: Article / Article
  • Volume: 44 Issue: 3
  • Publication Date: 2019
  • Doi Number: 10.1515/tjb-2018-0173
  • Journal Name: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
  • Journal Indexes: Science Citation Index Expanded, Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.379-387
  • Keywords: Ethyl glucuronide, Ethyl sulfate, Ethanol, Kinetics, Liquid chromatography-mass spectrometry, Polymorphism, UDP-GLUCURONOSYLTRANSFERASES, GENETIC POLYMORPHISMS, URINE, BLOOD, IDENTIFICATION, VOLUNTEERS, EXCRETION, PROFILES, SERUM

Abstract

Background and objective: Ethyl glucuronide (EtG) and ethyl sulfate (EtS), minor metabolites of ethanol, aid to forensic scientist and clinicians to determine recent ethanol uptake when ethanol elimination is occurred. Present study aimed to show (a) kinetics of EtG and EtS in blood and urine after 0.5 g/kg ethanol intake (b) peak concentrations and time of disappearance in Turkish people.