Joint Modeling Approach on Evaluating Time-Dependent CutOff Values for C-Reactive Protein in Mixed Intensive Care Unit Population

KONAR N. M., KARAİSMAİLOĞLU E., PORTAKAL AKÇİN O., PINAR A., DİKMEN Z. G., KARAAĞAOĞLU A. E.

CLINICAL LABORATORY, vol.66, no.9, pp.1725-1730, 2020 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 66 Issue: 9
  • Publication Date: 2020
  • Doi Number: 10.7754/clin.lab.2020.191239
  • Journal Name: CLINICAL LABORATORY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
  • Page Numbers: pp.1725-1730
  • Hacettepe University Affiliated: Yes

Abstract

Background: Serial C-reactive protein (CRP) biomarker values are frequently recorded from patients in adult intensive care units (ICU). The aim of this study was to assess the time-dependent diagnostic accuracy of repeated CRP measurements in predicting ICU mortality and determine the time-dependent cutoff values for this biomarker in mixed ICU population.