Carbon nanotube-chitosan modified disposable pencil graphite electrode for Vitamin B-12 analysis


KURALAY F., VURAL T., BAYRAM C., DENKBAŞ E. B., ABACI S.

COLLOIDS AND SURFACES B-BIOINTERFACES, vol.87, no.1, pp.18-22, 2011 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 87 Issue: 1
  • Publication Date: 2011
  • Doi Number: 10.1016/j.colsurfb.2011.03.030
  • Journal Name: COLLOIDS AND SURFACES B-BIOINTERFACES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.18-22
  • Keywords: Single walled carbon nanotubes, Chitosan, Biosensor, Disposable pencil graphite electrode, Vitamin B-12, DIRECT ELECTROCHEMISTRY, GLUCOSE-OXIDASE, COMPOSITE FILM, CYTOCHROME-C, BIOSENSOR, MATRIX, SENSOR, IMMOBILIZATION, ELECTROCATALYSIS, NANOCOMPOSITES
  • Hacettepe University Affiliated: Yes

Abstract

A single walled carbon nanotube-chitosan (SWCNT-chitosan) modified disposable pencil graphite electrode (PGE) was used in this study for the electrochemical detection of Vitamin B-12. Electrochemical behaviors of SWCNT-chitosan PGE and chitosan modified PGE were compared by using cyclic voltammetry (CV), square-wave voltammetry (SWV) and electrochemical impedance spectroscopy (EIS) techniques. SWCNT-chitosan modified electrode was also used for the quantification of Vitamin B-12 in pharmaceutical products. The results show that this electrode system is suitable for sensitive Vitamin B-12 analysis giving good recovery results. The surface morphologies of the SWCNT-chitosan PGE, chitosan modified PGE and unmodified PGE were characterized by using scanning electron microscopy (SEM). (C) 2011 Elsevier B.V. All rights reserved.