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GÜNDÜZ M. G., Isli F., El-Khouly A., Yildirim S., Fincan G. S. O., ŞİMŞEK R., ...More
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol.75, pp.258-266, 2014 (SCI-Expanded)
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Publication Type:
Article / Article
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Volume:
75
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Publication Date:
2014
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Doi Number:
10.1016/j.ejmech.2014.01.059
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Journal Name:
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
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Journal Indexes:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
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Page Numbers:
pp.258-266
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Keywords:
Acridinedione, Myorelaxant activity, Potassium channel, Pinacidil, POTASSIUM CHANNEL OPENERS, VASCULAR SMOOTH-MUSCLE, BLADDER CONTRACTIONS, ION CHANNELS, 1,1-DIOXIDE A-278637, ORGANIC-SYNTHESIS, PHARMACOLOGY, CALCIUM, 1,4-DIHYDROPYRIDINES, DIHYDROPYRIDINES
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Hacettepe University Affiliated:
Yes
Abstract
In this study a microwave-assisted method was applied for the synthesis of novel 9-(substituted indolyl)-3,4,6,7-tetrahydroacridine-1,8-(2H,5H,9H,10H)-dione derivatives. The structures of the compounds were confirmed by spectral methods including X-ray studies and elemental analysis.