Interleukin-10 gene transfer: Prevention of multiple organ injury in a murine cecal ligation and puncture model of sepsis

KABAY B., Kocaefe C., Baykal A., OEZDEN H., BAYCU C., ONER Z., ...More

WORLD JOURNAL OF SURGERY, vol.31, no.1, pp.105-115, 2007 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 31 Issue: 1
  • Publication Date: 2007
  • Doi Number: 10.1007/s00268-006-0066-9
  • Journal Name: WORLD JOURNAL OF SURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.105-115
  • Hacettepe University Affiliated: Yes

Abstract

Introduction: The aim of this study was to determine the effect of immunoregulatory cytokine interleukin-10 (IL-10) gene therapy on multiple organ injury (MOI) induced by a cecal ligation and puncture (CLP) model of sepsis in mice.