Behçet's Disease-related Budd–Chiari Syndrome Successfully Managed with anti-TNF Antibody: A Case Report and Review of the Literature

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ERUL E., Uzun G. S., KÖKSAL D., KESKİN O., UYSAL S., İNKAYA A. Ç., ...Daha Fazla

European Journal of Case Reports in Internal Medicine, cilt.9, sa.8, 2022 (Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 9 Sayı: 8
  • Basım Tarihi: 2022
  • Doi Numarası: 10.12890/2022_003515
  • Dergi Adı: European Journal of Case Reports in Internal Medicine
  • Derginin Tarandığı İndeksler: Scopus
  • Anahtar Kelimeler: Behçet's disease, bronchopleural fistula, Budd–Chiari syndrome, infliximab, vascular involvement
  • Hacettepe Üniversitesi Adresli: Evet

Özet

© EFIM 2022.Behçet's disease (BD) is multisystemic vasculitis with heterogeneous clinical manifestations. We describe the case of a 26-year-old man who presented with Budd–Chiari syndrome (BCS) related to BD. The patient received infliximab (IFX) due to the severity of vascular involvement. Subsequently, after IFX therapy, hospital-acquired pneumonia, trapped lung, and fungal infection of the lung and central nervous system developed as complications. The patient benefited from a second course of IFX and clinical remission was achieved following early identification and treatment of complications. Data on the presentation and prognosis of BCS related to BD are extremely limited. Our case report supports the growing evidence that anti-TNF antibody is a promising treatment for BD-related BCS.