An overview of nanofiber-based antibacterial drug design

ÇALAMAK S., SHAHBAZI R., EROĞLU İ., Gultekinoglu M., ULUBAYRAM K.

EXPERT OPINION ON DRUG DISCOVERY, vol.12, no.4, pp.391-406, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 12 Issue: 4
  • Publication Date: 2017
  • Doi Number: 10.1080/17460441.2017.1290603
  • Journal Name: EXPERT OPINION ON DRUG DISCOVERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.391-406
  • Keywords: Antibacterial, nanofibers, antibacterial drug delivery, advanced antibacterial, delivery systems, CORE-SHELL NANOFIBERS, CONTROLLED-RELEASE, ELECTROSPUN NANOFIBERS, STAPHYLOCOCCUS-AUREUS, ANTIBIOTIC-RESISTANCE, COMPOSITE NANOFIBERS, SILVER NANOPARTICLES, COAXIAL-ELECTROSPUN, VIVO PERFORMANCE, TOPICAL DELIVERY
  • Hacettepe University Affiliated: Yes

Abstract

Introduction: Conventional administration of antibacterial drugs to the human body can cause vital problems such as dose dependent systemic toxicity and bacterial resistance which prevent the healing process. In this regard, recent studies have been devoted to producing nanofiber based antibacterial drug delivery approaches which surpass bacterial resistance and toxicological issues.