Mutations in the gene for familial Mediterranean fever: do they predispose to inflammation?

Ozen S., Bakkaloglu A., Yilmaz E., Duzova A., Balci B., Topaloglu R., ...Daha Fazla

The Journal of rheumatology, cilt.30, sa.9, ss.2014-8, 2003 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 30 Sayı: 9
  • Basım Tarihi: 2003
  • Dergi Adı: The Journal of rheumatology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.2014-8
  • Anahtar Kelimeler: familial Mediterranean fever, carrier frequency, juvenile arthritis, BEHCETS-DISEASE, MEFV MUTATIONS, FREQUENCY, CARRIER, FMF, ADVANTAGE, SPECTRUM
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Objective. To analyze 70 individuals who were found to have the Mediterranean fever (MEFV) gene for the presence of definite familial Mediterranean fever (FMF) and to assess if they were prone to clinical and laboratory inflammation. We also prospectively evaluated 72 patients with childhood rheumatic diseases for the presence of MEFV mutations.