Synthesis and cytotoxicity studies on new pyrazole-containing oxime ester derivatives

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KARAKURT A., Bozbey I., USLU H., SARI S., ÖZDEMİR Z., ŞALVA E.

TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH, cilt.18, sa.6, ss.1315-1322, 2019 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 18 Sayı: 6
  • Basım Tarihi: 2019
  • Doi Numarası: 10.4314/tjpr.v18i6.24
  • Dergi Adı: TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1315-1322
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Purpose: To synthesize a series of new 1-(2-naphthyl)-2-(1H-pyrazol-1-yl)ethanone oxime ester derivatives (5-12) with potential anticancer properties, and to determine their cytotoxic effects in mouse fibroblast and human neuroblastoma cell lines.