Impact of cytokine genotype on cardiovascular surrogate markers in hemodialysis patients

Yilmaz R., ALTUN B., ÖZER N., HAZIROLAN T., Turgan C.

RENAL FAILURE, vol.32, no.7, pp.806-816, 2010 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 32 Issue: 7
  • Publication Date: 2010
  • Doi Number: 10.3109/0886022x.2010.494798
  • Journal Name: RENAL FAILURE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.806-816
  • Hacettepe University Affiliated: Yes

Abstract

Background/aims: Cytokine gene polymorphisms have been implicated as potential genetic risk factors for cardiovascular diseases (CVDs). Atherosclerosis and left ventricular hypertrophy (LVH) are surrogate markers for CVDs in uremic patients. The aim of this study was to assess the role of cytokine gene polymorphisms in carotid intima-media thickness (CIMT) and left ventricular mass index (LVMI) progression in nondiabetic hemodialysis (HD) patients.