Sclerotherapy with bleomycin does not adversely affect facial nerve function in children with cervicofacial cystic lymphatic malformation


KARAVELIOGLU A., TEMUÇİN Ç. M., TANYEL F. C., ÇİFTÇİ A. Ö., Senocak M. E., KARNAK İ.

JOURNAL OF PEDIATRIC SURGERY, cilt.45, sa.8, ss.1627-1632, 2010 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 45 Sayı: 8
  • Basım Tarihi: 2010
  • Doi Numarası: 10.1016/j.jpedsurg.2009.12.014
  • Dergi Adı: JOURNAL OF PEDIATRIC SURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1627-1632
  • Anahtar Kelimeler: Bleomycin, Sclerotherapy, Facial nerve, EMG, Cystic hygroma, Cystic lymphangioma, Lymphatic malformation, Neck, Child, INTRACYSTIC CHEMOTHERAPY, CRANIOPHARYNGIOMA, LYMPHANGIOMA, EXPERIENCE, PARALYSIS, THERAPY, HYGROMA, NECK, HEAD
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Background and Purpose: Sclerotherapy with bleomycin sulfate (BS) is currently used in the management of cervicofacial cystic lymphatic malformations in children. Neurotoxic adverse effects of BS after intraventricular or intracavitary administration have been reported; however, the effects of intralesionally administered BS on the adjacent peripheral neural structures have not been previously investigated. The authors conducted a clinical experimental study to evaluate facial nerve function in children who have undergone BS sclerotherapy for cervicofacial cystic lymphatic malformation.