Identification of the difference in extracellular matrix and adhesion molecules of cultured human gingival fibroblasts versus juvenile hyaline fibromatosis gingival fibroblasts using cDNA microarray analysis.

Hakki, SS; Balci, BANU; Hakki, EE; Yilmaz, E; Nohutcu, RM

doi:10.1902/jop.2005.76.12.2244

Identification of the difference in extracellular matrix and adhesion molecules of cultured human gingival fibroblasts versus juvenile hyaline fibromatosis gingival fibroblasts using cDNA microarray analysis.

Atıf İçin Kopyala

Hakki S., Balci B., Hakki E., Yilmaz E., Nohutcu R.

Journal of periodontology, cilt.76, sa.12, ss.2244-53, 2005 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 76 Sayı: 12
Basım Tarihi: 2005
Doi Numarası: 10.1902/jop.2005.76.12.2244
Dergi Adı: Journal of periodontology
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.2244-53
Hacettepe Üniversitesi Adresli: Evet

Özet

Background: A difference from the normal range in collagen profile and perivascular hyaline deposition in the dermis and gingiva has been demonstrated histopathologically in juvenile hyaline fibromatosis (JHF), which is an autosomal recessive disease. The aim of this study was to understand the mechanism of gingival overgrowth in JHF, and to observe differences in the expression of genes regulating extracellular matrix organization.