Familial Hypercholesterolemia: Global Burden and Approaches

Tokgozoglu L., KAYIKÇIOĞLU L. M.

CURRENT CARDIOLOGY REPORTS, cilt.23, sa.10, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 23 Sayı: 10
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1007/s11886-021-01565-5
  • Dergi Adı: CURRENT CARDIOLOGY REPORTS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CAB Abstracts, EMBASE, MEDLINE
  • Anahtar Kelimeler: Familial hypercholesterolemia, Guidelines, Low-density lipoprotein cholesterol, Lipoprotein(a), LDL-APHERESIS, CARDIOVASCULAR EVENTS, ATHEROSCLEROSIS, CHOLESTEROL, EVOLOCUMAB, CLINICIAN, EFFICACY, RISK, INHIBITION, ALIROCUMAB
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Purpose of Review Familial hypercholesterolemia (FH) is the most common genetic metabolic disorder characterized by markedly elevated LDL-C levels from birth leading to atherosclerotic cardiovascular disease (ASCVD) and premature deaths. The purpose of this review is to share the current knowledge in the diagnosis, risk estimation, and management of patients with FH in the light of recent evidence and guideline recommendations.