Nationwide Experience With Off-Label Use of Interleukin-1 Targeting Treatment in Familial Mediterranean Fever Patients

AKAR, SERVET; Cetin, Pinar; KALYONCU, UMUT; KARADAĞ, ÖMER; Sari, Ismail; Cinar, Muhammed; Yilmaz, Sedat; Onat, Ahmet; Kisacik, Bunyamin; ERDEN, ABDULSAMET; Balkarli, Ayse; KÜÇÜKŞAHİN, ORHAN; Oner, Sibel; Senel, Soner; TUFAN, ABDURRAHMAN; DİRESKENELİ, RAFİ; Oksuz, Ferhat; PEHLİVAN, YAVUZ; Bayindir, Ozun; KESER, GÖKHAN; AKSU, KENAN; Omma, Ahmet; KAŞİFOĞLU, TİMUÇİN; Unal, Ali; Yildiz, Fatih; Balci, Mehmet; Yavuz, Sule; ERTEN, ŞÜKRAN; Ozgen, Metin; Sayarlioglu, Mehmet; DOĞRU, Atalay; Yildirim, Gozde; Oner, Fatma; Tezcan, Mehmet; Pamuk, Omer; ÖNEN, FATOŞ

doi:10.1002/acr.23446

Nationwide Experience With Off-Label Use of Interleukin-1 Targeting Treatment in Familial Mediterranean Fever Patients

Atıf İçin Kopyala

AKAR S., Cetin P., KALYONCU U., KARADAĞ Ö., Sari I., Cinar M., ...Daha Fazla

ARTHRITIS CARE & RESEARCH, cilt.70, sa.7, ss.1090-1094, 2018 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 70 Sayı: 7
Basım Tarihi: 2018
Doi Numarası: 10.1002/acr.23446
Dergi Adı: ARTHRITIS CARE & RESEARCH
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1090-1094
Hacettepe Üniversitesi Adresli: Evet

Özet

ObjectiveApproximately 30-45% of patients with familial Mediterranean fever (FMF) have been reported to have attacks despite colchicine treatment. Currently, data on the treatment of colchicine-unresponsive or colchicine-intolerant FMF patients are limited; the most promising alternatives seem to be anti-interleukin-1 (anti-IL-1) agents. Here we report our experience with the off-label use of anti-IL-1 agents in a large group of FMF patients.