Effects of clozapine and haloperidol treatment on plasma concentrations of androgen hormones and androgendependent organ changes in rats

Samadi A., Isikhan S., Ansari M. H. K., Samadi M., SABUNCUOĞLU S.

INDIAN JOURNAL OF PHARMACOLOGY, cilt.51, sa.4, ss.269-275, 2019 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 51 Sayı: 4
  • Basım Tarihi: 2019
  • Doi Numarası: 10.4103/ijp.ijp_145_18
  • Dergi Adı: INDIAN JOURNAL OF PHARMACOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.269-275
  • Hacettepe Üniversitesi Adresli: Evet

Özet

OBJECTIVES: Metabolic and endocrine adverse effects are among the most concerning unfavorable consequences of commonly used psychotropic drugs. The present research was planned to assess and determine the effects of haloperidol and clozapine on testosterone, cortisol, and corticosterone levels and also their influence on androgen-dependent organs in adult male Wistar rats.