Recent Developments in CE-MS Based Metabolomics
CURRENT ANALYTICAL CHEMISTRY, cilt.17, sa.9, ss.1229-1242, 2021 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Derleme
- Cilt numarası: 17 Sayı: 9
- Basım Tarihi: 2021
- Doi Numarası: 10.2174/1573411016999200709133339
- Dergi Adı: CURRENT ANALYTICAL CHEMISTRY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Biotechnology Research Abstracts, Chemical Abstracts Core
- Sayfa Sayıları: ss.1229-1242
- Anahtar Kelimeler: Biomarkers, capillary electrophoresis-mass spectrometry, metabolome, metabolomics, review, XCMS, NUCLEAR-MAGNETIC-RESONANCE, ELECTROPHORESIS-MASS SPECTROMETRY, CAPILLARY-ELECTROPHORESIS, METABOLITE IDENTIFICATION, SAMPLE PREPARATION, HEPATOCELLULAR-CARCINOMA, BIOMARKER DISCOVERY, URINE METABOLOME, BLADDER-CANCER, VALIDATION
- Hacettepe Üniversitesi Adresli: Evet
Özet
Background: Metabolomics has gained importance in clinical applications over the last decade. Metabolomics studies are significant because the systemic metabolome is directly affected by disease conditions. Metabolome-based biomarkers are actively being developed for early diagnosis and to indicate the stage of specific diseases. Additionally, understanding the effect of an intervention on a living organism at the molecular level is a crucial strategy for understanding novel or unexpected biological processes.