Capecitabine Induced Hand-Foot Syndrome: A Systematic Review of Case Reports


ARAS E., Tecen-Yucel K., Bayraktar-Ekincioglu A., Gullu I.

CLINICAL AND EXPERIMENTAL HEALTH SCIENCES, vol.9, no.2, pp.178-191, 2019 (Peer-Reviewed Journal) identifier

  • Publication Type: Article / Review
  • Volume: 9 Issue: 2
  • Publication Date: 2019
  • Doi Number: 10.33808/clinexphealthsci.469538
  • Journal Name: CLINICAL AND EXPERIMENTAL HEALTH SCIENCES
  • Journal Indexes: Emerging Sources Citation Index, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.178-191

Abstract

Objective: Capecitabine, a prodrug of 5-fluorouracil, is currently used in the treatment of metastatic colorectal and breast cancers. The aim of this study was to review the pharmacological mechanisms, treatment strategies, and documented case reports of capecitabine-induced hand-foot syndrome (HFS).