Effects of molecular weight and ratio of guluronic acid to mannuronic acid on the antioxidant properties of sodium alginate fractions prepared by radiation-induced degradation

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Sen M.

APPLIED RADIATION AND ISOTOPES, cilt.69, ss.126-129, 2011 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 69
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1016/j.apradiso.2010.08.017
  • Dergi Adı: APPLIED RADIATION AND ISOTOPES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.126-129
  • Anahtar Kelimeler: Radiation induced degradation, Sodium alginate, Antioxidant properties, IN-VITRO, CHITOSAN, POLYSACCHARIDES, IRRADIATION, DERIVATIVES, CARRAGEENAN, PLANTS, MODEL
  • Hacettepe Üniversitesi Adresli: Evet

Özet

In this study the effects of the molecular weight and ratio of guluronic acid (G) to mannuronic acid (M) G/M of some sodium alginate (NaAlg) fractions on their antioxidative properties were investigated Low-molecular-weight-fractions with various G/M were prepared by gamma radiation-induced degradation of NaAlg Change in their molecular weight was monitored Antioxidant properties of the fractions with various molecular weight and G/M were evaluated by determining the scavenging ability of 1 1-diphenyl-2-picrylhydrazyl free radical (DPPH) 50% inhibition concentrations of the 50 kGy-irradiated NaAlgs having molecular weights of 20 5 17 7 and 16 0 kDa were found to be 11 0 18 0 and 24 0 mg/ml respectively whereas the fractions of the same molecular weight with a lower G/M exhibited a better DPPH scavenging activity The results demonstrated that its molecular weight and G/M were Important factors in controlling the antioxidant properties of NaAlg (C) 2010 Elsevier Ltd All rights reserved

In this study, the effects of the molecular weight and ratio of guluronic acid (G) to mannuronic acid (M), G/M, of some sodium alginate (NaAlg) fractions on their antioxidative properties were investigated. Low-molecular-weight-fractions with various G/M were prepared by gamma radiation-induced degradation of NaAlg. Change in their molecular weight was monitored. Antioxidant properties of the fractions with various molecular weight and G/M were evaluated by determining the scavenging ability of 1,1-diphenyl-2-picrylhydrazyl free radical (DPPHradical dot). 50% inhibition concentrations of the 50 kGy-irradiated NaAlgs having molecular weights of 20.5, 17.7, and 16.0 kDa were found to be 11.0, 18.0, and 24.0 mg/ml, respectively, whereas the fractions of the same molecular weight with a lower G/M exhibited a better DPPHradical dot scavenging activity. The results demonstrated that its molecular weight and G/M were important factors in controlling the antioxidant properties of NaAlg.