Serum Levels of Annexin A2 as a Candidate Biomarker for Hepatic Fibrosis in Patients With Chronic Hepatitis B

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Kolgelier S., Demir N. A., İNKAYA A. Ç., Sumer S., OZCIMEN S., Demir L. S., ...Daha Fazla

HEPATITIS MONTHLY, cilt.15, sa.10, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 15 Sayı: 10
  • Basım Tarihi: 2015
  • Doi Numarası: 10.5812/hepatmon.30655
  • Dergi Adı: HEPATITIS MONTHLY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: Annexin A2, Hepatitis B, Chronic, Liver Fibrosis, Biological Marker, HEPATOCELLULAR-CARCINOMA, NATURAL-HISTORY, VIRUS INFECTION, LIVER FIBROSIS, EXPRESSION, MARKER
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Background: Hepatologists have studied serologic markers of liver injury for decades. Annexins are a prominent group of such markers and annexin A2 (AnxA2) is one of the best characterized annexins. AnxA2 inhibits HBV polymerase among other functions. Its expression is up-regulated in regenerative hepatocytes.