The effect of CD14-C159T genotypes on the cytokine response to endotoxin by peripheral blood mononuclear cells from asthmatic children

---

Copy For Citation

Keskin O., Birben E., Sackesen C., Soyer O. U., Alyamac E., Karaaslan C., ...More

ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY, vol.97, no.3, pp.321-328, 2006 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 97 Issue: 3
• Publication Date: 2006
• Doi Number: 10.1016/s1081-1206(10)60796-x
• Journal Name: ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.321-328
• Hacettepe University Affiliated: Yes

Abstract

Background: A C-T polymorphism at position 159 in the promoter of CD14 (C-159T) modulates the cellular response to endotoxin and significantly influences total IgE levels. The effect of this genetic variant on the cytokine response of the inflammatory cells is incompletely understood.