Expression Profiles of the Individual Genes Corresponding to the Genes Generated by Cytotoxicity Experiments with Bortezomib in Multiple Myeloma


Creative Commons License

GHASEMİ m., ALPSOY S., TÜRK TÜRK S., MALKAN Ü. Y., ATAKAN Ş., HAZNEDAROĞLU İ. C., ...Daha Fazla

TURKISH JOURNAL OF HEMATOLOGY, cilt.33, sa.4, ss.286-292, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 33 Sayı: 4
  • Basım Tarihi: 2016
  • Doi Numarası: 10.4274/tjh.2015.0145
  • Dergi Adı: TURKISH JOURNAL OF HEMATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.286-292
  • Anahtar Kelimeler: Myeloma and other plasma cell dyscrasias, Neoplasia, Cytogenetics, Gene therapy, Molecular hematology, COST-EFFECTIVENESS, IN-SILICO, DRUG-SENSITIVITY, CANCER-CELLS, THERAPY, PLASMACYTOMAS, DEXAMETHASONE, LENALIDOMIDE, MALIGNANCIES, SIMULATION
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Objective: Multiple myeloma (MM) is currently incurable due to refractory disease relapse even under novel anti-myeloma treatment. In silico studies are effective for key decision making during clinicopathological battles against the chronic course of MM. The aim of this present in silico study was to identify individual genes whose expression profiles match that of the one generated by cytotoxicity experiments for bortezomib.