Stimulation of lymphocyte proliferation and inhibition of nitric oxide production by aqueous Urtica dioica extract

Harput U., Saracoglu I., Ogihara Y.

PHYTOTHERAPY RESEARCH, cilt.19, sa.4, ss.346-348, 2005 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 19 Sayı: 4
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1002/ptr.1686
  • Dergi Adı: PHYTOTHERAPY RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.346-348
  • Anahtar Kelimeler: Urtica dioica, Urticaceae, immunomodulation, antiinflammation, T-lymphocytes, nitric oxides, macrophages, IN-VITRO, ROOTS
  • Hacettepe Üniversitesi Adresli: Evet

Özet

The immunomodulatory and antiinflammatory activities of aqueous Urtica dioica extract were investigated for their effect on the mitogenic response of murine splenocytes and nitric oxide production by murine peritoneal macrophages in vitro. It was found that this extract stimulated the proliferation of T-lymphocytes and suppressed NO production in lipopolysaccharide - stimulated macrophages without affecting cell viability. Copyright (c) 2005 John Wiley & Sons, Ltd.