Comparison of the Effect of Platelet-Rich Plasma and Simvastatin on Healing of Critical-Size Calvarial Bone Defects

Seyhan, Nevra; Keskin, Suat; Aktan, Murat; AVUNDUK, MUSTAFA; ŞENGELEN, MELTEM; Savaci, Nedim

doi:10.1097/scs.0000000000002728

Comparison of the Effect of Platelet-Rich Plasma and Simvastatin on Healing of Critical-Size Calvarial Bone Defects

Seyhan N., Keskin S., Aktan M., AVUNDUK M. C., ŞENGELEN M., Savaci N.

JOURNAL OF CRANIOFACIAL SURGERY, vol.27, no.5, pp.1367-1370, 2016 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 27 Issue: 5
Publication Date: 2016
Doi Number: 10.1097/scs.0000000000002728
Journal Name: JOURNAL OF CRANIOFACIAL SURGERY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.1367-1370
Hacettepe University Affiliated: Yes

Abstract

Objective: In previous studies, it has been shown that both simvastatin (chlolesterollowering drug) and platelet-rich plasma (PRP) were capable of promoting bone formation. The aim of this study was to compare the effects of PRP and simvastatin on healing of critical-size bone defects.