Akademik Veri Yönetim Sistemi
ANDAÇ A. M. (Yürütücü)
TÜBİTAK Projesi, 1001 - Bilimsel ve Teknolojik Araştırma Projelerini Destekleme Programı, 2022 - 2024
In recent years, with the start of small-scale device production thanks to nanotechnological approaches, interest in biosensor systems that can detect more than one molecule simultaneously, have high selectivity and sensitivity, and allow measurement at low concentrations has been increasing. Biosensors are portable devices that can be detected easily, at low cost, quickly, on-site, without expert personnel, and reliably, even in trace amounts, in the environment (solid, liquid, gaseous environment) of the molecule to be detected. Moreover, significant developments have been achieved in this field by using fully synthetic plastic receptors such as semi-synthetic ligands and molecularly imprinted polymers synthesized by protein engineering instead of biological receptors used in biosensors.
Within the scope of this project, directed plastic receptors synthesis will be done for real-time detection of airborne Covid-19 mutant viruses. Characterization and binding studies will be carried out for virus detection from aqueous media with nanofilm surfaces containing oriented plastic receptors. Oriented plastic receptor-containing nanofilm surfaces will be characterized by UV-Vis spectrometer, Contact Angle measurement, Fourier Transform Infrared Spectroscopy (FTIR), Micro Computed Tomography (MCT), Scanning Electron Microscopy (SEM) and Atomic Force Microscopy (AFM). The sensitivity, accuracy and selectivity of the oriented plastic receptor-containing nanofilm sensor for virus detection in aqueous media will be tested. In this context, continuous monitoring of water for SARS-Cov-2 is very important in terms of establishing early warning systems before an epidemic starts in case the infection reoccurs. Finally, the thermal stability and reproducibility of the nanofilm sensor containing the oriented plastic receptor will be tested.