Ögrenim Bilgisi


Doktora
2017 - Devam Ediyor
Hacettepe Üniversitesi, Sağlık Bilimleri Enstitüsü, Analitik Kimya, Türkiye

Yüksek Lisans
2014 - 2017
Hacettepe Üniversitesi, Sağlık Bilimleri Enstitüsü, Analitik Kimya , Türkiye

Lisans
2007 - 2012
Hacettepe Üniversitesi, Fen Fakültesi, Kimya, Türkiye

Akademik Unvanlar / Görevler


Araştırma Görevlisi
2018 - Devam Ediyor
Hacettepe Üniversitesi, Eczacılık Fakültesi, Temel Eczacılık Bilimleri Bölümü

Desteklenen Projeler

  1. KORKUSUZ F., TURHAN E., ÇELEBİER M., KARAÇOBAN L., KAPLAN O., Gizer M., KORKUSUZ P., Yükseköğretim Kurumları Destekli Proje, Sinoviyum ve Yağ Dokudan Elde Edilen Allojenik Mezenkimal Kök Hücrelerin Normal ve Osteoartritli Kondrosit Hücre Hatları Üzerine Olan Etki ve Etki Mekanizmasının İnvitro Ortamda İncelenmesi, 2020 - 2022
  2. BABAOĞLU M. Ö., VANLI TONYALI N., ŞAHİN UYGUR D., Ongun M. C., BAŞCI AKDUMAN N. E., ÇELEBİER M., YÜCEL A., KAPLAN O., Yükseköğretim Kurumları Destekli Proje, Preeklampside ve Gestasyonel Hipertansiyonda CYP4F2, 4F3, 4A11, 2J2, 2C9, 2C19, Solubl Epoksit Hidrolaz Enzimleri ile İlaç Transporteri MDR1 Genetik Polimorfizmlerinin Etkileri, 2019 - 2021

SCI, SSCI ve AHCI İndekslerine Giren Dergilerde Yayınlanan Makaleler

  1. Effects of genetic polymorphisms of CYP2J2, CYP2C9, CYP2C19, CYP4F2, CYP4F3 and CYP4A11 enzymes in preeclampsia and gestational hypertension
    Ongun M. C., Tonyali N. V., KAPLAN O., DEĞER İ., ÇELEBİER M., BAŞCI AKDUMAN N. E., Sahin D., Yucel A., BABAOĞLU M. Ö.
    Placenta, cilt.137, ss.88-95, 2023 (SCI-Expanded)
  2. Pharmacometabolomic assessment of vitamin E loaded human serum albumin nanoparticles on HepG2 cancer cell lines
    Şenol Y., KAPLAN O., VARAN C., Demirtürk N., Öncül S., Fidan B. B., ERCAN A., BİLENSOY E., ÇELEBİER M.
    Journal of Drug Delivery Science and Technology, cilt.79, 2023 (SCI-Expanded)
  3. Plasma irisin and metabolomic response differ between concentric and isometric exercise Effets différents de l'exercice concentrique et de l'exercice isométrique sur l'irisine plasmatique et la réponse métabolomique
    KARA Ö. S., ERCAN A., ÇELEBİER M., KAPLAN O., ÖNCÜL S., KORKUSUZ F.
    Science and Sports, cilt.37, sa.7, ss.610-617, 2022 (SCI-Expanded)
  4. A combination of Q-TOF LC/MS and LC-MS/MS based metabolomics in pediatric-onset multiple sclerosis demonstrates potential biomarkers for unclassified patients
    Solmaz İ., KAPLAN O., ÇELEBİER M., LAY İ., Anlar B.
    Turkish Journal of Medical Sciences, cilt.52, sa.4, ss.1299-1310, 2022 (SCI-Expanded)
  5. Q-tof lc/ms-based untargeted metabolomics approach to evaluate the effect of folate-conjugated cyclodextrins on triple-negative breast cancer cells
    Varol I., KAPLAN O., Erdoğar N., Öncül S., Nielsen T. T., ERCAN A., BİLENSOY E., ÇELEBİER M.
    Current Pharmaceutical Analysis, cilt.17, sa.10, ss.1272-1281, 2021 (SCI-Expanded)
  6. Bioanalytical Method Validation of an RP-HPLC Method for Determina-tion of Rifampicin in Liver Perfusion Studies
    İZAT N., KAPLAN O., ÇELEBİER M., ŞAHİN S.
    CURRENT PHARMACEUTICAL ANALYSIS, cilt.17, sa.7, ss.919-925, 2021 (SCI-Expanded)
  7. UPLC-Q-TOF/MS based Untargeted Metabolite and Lipid Analysis on Premature Ovarian Insufficiency Plasma Samples
    Tasci Y., Findik R. B., Pekcan M. K., KAPLAN O., ÇELEBİER M.
    CURRENT PHARMACEUTICAL ANALYSIS, cilt.17, sa.4, ss.474-483, 2021 (SCI-Expanded)
  8. Predictive biomarkers of IgA vasculitis with nephritis by metabolomic analysis
    DEMİR S., KAPLAN O., ÇELEBİER M., SAĞ E., BİLGİNER Y., LAY İ., ÖZEN S.
    Seminars in Arthritis and Rheumatism, cilt.50, sa.6, ss.1238-1244, 2020 (SCI-Expanded)
  9. Polycystic ovary syndrome in adolescents: Q-TOF LC/MS analysis of human plasma metabolome
    ÇELEBİER M., KAPLAN O., Özel Ş., Engin-Üstün Y.
    Journal of Pharmaceutical and Biomedical Analysis, cilt.191, 2020 (SCI-Expanded)
  10. Past, present and future of metabolomic studies Metabolomik çalışmaların dünü, bugünü ve yarını
    KAPLAN O., ÇELEBİER M.
    Turkiye Klinikleri Journal of Medical Sciences, cilt.40, sa.3, ss.366-374, 2020 (SCI-Expanded)
  11. Discovery of Michael acceptor containing 1,4-dihydropyridines as first covalent inhibitors of L-/T-type calcium channels
    Cevher H. A., Schaller D., Gandini M. A., KAPLAN O., Gambeta E., Zhang F. X., ÇELEBİER M., Tahir M. N., Zamponi G. W., Wolber G., et al.
    BIOORGANIC CHEMISTRY, cilt.91, 2019 (SCI-Expanded)
  12. Global omics strategies to investigate the effect of cyclodextrin nanoparticles on MCF-7 breast cancer cells
    ERCAN A., ÇELEBİER M., VARAN G., ÖNCÜL S., Nenni M., KAPLAN O., BİLENSOY E.
    European Journal of Pharmaceutical Sciences, cilt.123, ss.377-386, 2018 (SCI-Expanded)

Diğer Dergilerde Yayınlanan Makaleler

  1. Comparison of Different Sample Preparation Techniques for Untargeted Metabolomics Utilizing Q-TOF LC/MS and MetaboAnalyst 4.0
    Kaplan O., Koçak E., Çelebier M.
    Current Metabolomics and Systems Biology, cilt.8, ss.53-60, 2021 (Hakemli Dergi)
  2. Evaluation of Recent Data Processing Strategies on Q-TOF LC/MS Based Untargeted Metabolomics
    KAPLAN O., ÇELEBİER M.
    MASS SPECTROMETRY LETTERS, cilt.11, sa.1, ss.1-5, 2020 (ESCI)
  3. Liquid-liquid extraction and ultrafiltration based sample preparation technique for Q-TOF LC/MS analysis of non-polar metabolites in human plasma samples
    KOÇAK E., KAPLAN O., ÇELEBİER M.
    Journal of Research in Pharmacy, cilt.24, sa.1, ss.38-43, 2020 (ESCI)
  4. Comparison of cell lysis techniques via q-tof lc/ms
    KAPLAN O., ÖNCÜL S., ERCAN A., ÇELEBİER M.
    Mass Spectrometry Letters, cilt.11, sa.2, ss.36-40, 2020 (ESCI)
  5. Determination of the physicochemical properties of piroxicam
    ÇELEBİER M., NENNİ M., KAPLAN O., AKGEYİK E., KAYNAK M. S., ŞAHİN S.
    TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES, cilt.0, sa.0, 2019 (Scopus)

Hakemli Kongre / Sempozyum Bildiri Kitaplarında Yer Alan Yayınlar

  1. Validation of an HPLC method for the determination of talazoparib from nanoparticle formulations
    Taş B., Akdağ Çaylı Y., Aytekin E., Pehlivan S., Öner L., Kaplan O.
    3rd International Gazi Pharma Symposium Series (GPSS-2021), 8 - 10 Eylül 2021, ss.1-2
  2. AN INNOVATIVE SAMPLE PREPARATION TECHNIQUE TO EVALUATE THE DIFFERENCES IN METABOLOME LEVELS FOR SYNOVIA AND FAT TISSUES
    KARAÇOBAN L., KAPLAN O., MENDERES Y., ÇELEBİER M., KORKUSUZ F.
    European Orthopaedic Research Society 28th Annual Meeting Congress, İzmir, Türkiye, 17 - 18 Eylül 2020
  3. Bioanalytical Validation of an HPLC Method for the Analysis of Rifampicin Accumulation in Rat Liver
    İzat N., Kir F., Kaplan O., Çelebier M., Şahin S.
    8. BBBB International Conference on Pharmaceutical Sciences (8.BBBB 2019), İzmir, Türkiye, 14 - 16 Ekim 2019, ss.332-333
  4. Comparison of different sample preparation techniques on human plasma samples for Q-TOF LC/MS based metabolite profiling
    ÇELEBİER M., KAPLAN O., KOÇAK E.
    Euroanalysis 2019, İstanbul, Türkiye, 1 - 05 Temmuz 2019
  5. Comparison of Metabolite Extraction Techniques for LC/MS Based Metabolomics on Human Blood Plasma
    KAPLAN O., KOÇAK E., ÇELEBİER M.
    International Multisciplinary Symposium on Drug Research Development - DRD 2019, Malatya, Türkiye, 1 - 03 Temmuz 2019
  6. Is It Possible To Use Pooled Plasma Samples For Large-Scale Human Metabolomic Studies? A Comparison Of The Metabolite Profiles Of Pooled Plasma Samples With Random Individual Samples Using Q-TOF LC/MS
    ÇELEBİER M., KAPLAN O., OZEL Ş., ÜSTÜN Y., KOÇAK E.
    1st International Congress on Analytical and Bioanalytical Chemistry, Antalya, Türkiye, 27 - 30 Mart 2019
  7. A Metabolomic Study to Investigate the Effect of Folate Conjugated Nanoparticles on Triple Negative Breast Cancer Cells
    ERCAN A., ÇELEBİER M., varol ı., KAPLAN O., Varan G., ÖNCÜL S., KOÇAK E., BİLENSOY E.
    EUFEPS Annual Meeting 2019 PERSONALIZED MEDICINES,TARGETED THERAPIES,PRECISION DRUG DELIVERY, 6 - 08 Mart 2019
  8. The effect of polycationic amphiphilic cyclodestrin nanoparticles on mda-mb cancer cells: A metabolomic approach to understand the mechanism
    ÇELEBİER M., KAPLAN O., VARAN G., ÖNCÜL S., KOÇAK E., ERCAN A., BİLENSOY E.
    12 th International symposium on pharmaceutical sciences, 26 Haziran 2018
  9. GENOMIC AND METABOLOMIC STUDIES OF POLYCATIONIC AMPHIPHILIC CYCLODEXTRIN NANOPARTICLESON HEPG2 CELL LINE
    ERCAN A., ÇELEBİER M., Varan G., ÖNCÜL S., KOÇAK E., KAPLAN O., BİLENSOY E.
    EUFEPS Annual Meeting 2018 Crossing Barriers for Future Medicines, 24 - 26 Mayıs 2018

Metrikler





Araştırma Alanları

Kimya, Analitik Kimya, Kromatografi, Kütle Spektroskopisi, Temel Bilimler