Aluminium in cosmetics and personal care products.

Sanajou S., Şahin G., Baydar T.

Journal of applied toxicology : JAT, cilt.41, sa.11, ss.1704-1718, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 41 Sayı: 11
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1002/jat.4228
  • Dergi Adı: Journal of applied toxicology : JAT
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Aerospace Database, Applied Science & Technology Source, Aqualine, Aquatic Science & Fisheries Abstracts (ASFA), BIOSIS, CAB Abstracts, Chemical Abstracts Core, Chimica, Communication Abstracts, EMBASE, Environment Index, MEDLINE, Metadex, Pollution Abstracts, Veterinary Science Database, Civil Engineering Abstracts
  • Sayfa Sayıları: ss.1704-1718
  • Anahtar Kelimeler: aluminium, Alzheimer's disease, antiperspirant, cancer, personal care products, BREAST-CANCER, ALZHEIMERS-DISEASE, SAFETY ASSESSMENT, ZIRCONIUM COMPLEX, DIFFERENT PHASES, HEALTH-RISKS, LIFE-TERM, ANTIPERSPIRANTS, EXPOSURE, TISSUE
  • Hacettepe Üniversitesi Adresli: Evet

Özet

Usage of inorganic ingredients like aluminium salts in cosmetics and personal care products has been a concern for producers and consumers. Although aluminium is used to treat hyperhidrosis, some worries have been raised about aluminium's role in breast cancer, breast cyst and Alzheimer's disease. The human population is exposed to aluminium from vaccines, diet, and drinking water, but the frequent use of aluminium-based cosmetics might add additional local exposure. This paper reviews literature to determine if aluminium-based products may pose potential harm to the body. The dermal absorption of aluminium is not widely understood. It is not yet known whether aluminium can travel from the skin to brain to cause Alzheimer's disease. Aluminium may cause gene instability, alter gene expression or enhance oxidative stress, but the carcinogenicity of aluminium has not been proved yet. Until now, epidemiological researches were based on oral information, which lacks consistency, and the results are conflicting. Future studies should target real-life-based long-time exposure to antiperspirants and other aluminium-containing cosmetics and personal care products.